MatriXpec™ hydrogels are developed to offer tissue-specific microenvironments for 3D cell culture. MatriXpec™ hydrogels allow running experiments in truly representative substrates that mimic the biological clues of the native extracellular matrix.
Besides the thermocrosslinkable hydrogel, MatriXpec™ Thermo, we also offer MatriXpec™ Photo, which allow UV photocrosslinking, offering an optimal combination of biochemical and biomechanical properties for bioprinting 3D constructs based on tissue-specific microenvironments.
MatriXpec™ Thermo and MatriXpec™ Photo are currently available for the following tissues:
Adipose, Bone, Brain, Cartilage, Colon, Kidney, Liver, Lung, Muscle, Myocardium, Pancreas, Skin, Spleen, Stomach, and Vascular.
Why MatriXpec™ Hydrogels?
Each version of MatriXpec™ - currently available for 15 different tissues - contains hundreds of tissue-specific extracellular matrix proteins derived from the native tissue. It means all and only the ECM proteins of each tissue will be present, leading to a unique combination found only in the tissue microenvironment itself.
DIRECTS CELL BEHAVIOUR AND DIFFERENTIATION
Due to the very particular composition of each version of MatriXpec™, it is possible to use our hydrogels to direct cell behavior and differentiation. The combination of tissue-specific proteins and biomechanical properties produce clues that cells interpret and react to, ultimately modulating their ability to proliferate, migrate and differentiate.
SUPPORTS 3D VASCULAR NETWORK FORMATION
MatriXpec™ hydrogels allow the formation of three-dimensional vascular networks when mixed with endothelial cells. This possibility paves the way for larger, clinically relevant, biofabricated tissues.