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MatriXpec™
Tissue-specific hydrogels for 3D cell culture and bioprinting
MatriXpec™ is TissueLabs’ line of tissue-specific biomaterials derived from decellularized extracellular matrix (dECM), designed to provide physiologically relevant microenvironments for 3D cell culture and bioprinting by mimicking the native biochemical and mechanical properties of each tissue.
MatriXpec™ hydrogels support a wide range of biofabrication methods and are compatible with both extrusion and light-based bioprinters, as well as organoid and 3D cell culture workflows.
The portfolio includes:
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MatriXpec™ Thermo is thermo-crosslinkable, ideal for 3D cell culture and FRESH bioprinting.
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MatriXpec™ Photo enables UV photocrosslinking for precise, support-free bioprinting.
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MatriXpec™ Ionic uses ionic crosslinking to enhance flexibility for tissue bioprinting.
All versions are vailable for 15 distinct tissue types — Adipose, Bone, Brain, Cartilage, Colon, Kidney, Liver, Lung, Muscle, Myocardium, Pancreas, Skin, Spleen, Stomach, and Vascular tissues. For research use only.
Tissue-Specific Microenvironments
Derived from decellularized tissue extracellular matrix, MatriXpec™ offers mimetic tissue-specific environments, unlike generic hydrogels.
Versatile for Multiple Applications
Adapts to various uses, including multiple bioprinting techniques, 3D cell culture, and preclinical animal studies, making it ideal for a range of tissue engineering needs.
Directs Cell Behavior and Differentiation
Provides tissue-specific cues that can guide cell behavior and promote differentiation, ensuring more accurate and functional tissue formation in 3D cultures and bioprinting applications.
Enhanced Vascularization
Supports the formation of vascular networks, promoting the development of complex, well-perfused tissues.
Reproducible
Ensures consistent and reliable results across experiments, providing high reproducibility for research and industrial applications
Low Immunogenicity
Designed to minimize immune responses, making it safe for implantation in animal models and suitable for preclinical in vivo studies.
Available for 15 Different Tissues
Adipose
Kidney
Pancreas
Bone
Liver
Skin
Brain
Lung
Spleen
Cartilage
Muscle
Stomach
Colon
Myocardium
Vascular
Comparison
Feature | MatriXpec™ Thermo | MatriXpec™ Photo | MatriXpec™ Ionic |
|---|---|---|---|
Composition | ECM proteins | ECM proteins and methacrylate groups | ECM proteins and alginate |
Crosslinking Mechanism | Heating (37ºC) | Exposure to light (405nm) | Contact with calcium solution |
3D Cell Culture | ✔ | ✔ | ✔ |
Extrusion-based Bioprinting | Only FRESH | ✔ | ✔ |
Light-based Bioprinting | No | ✔ | No |
Delivery Platform
(for cells, growth factors, nucleic acids, etc) | ✔ | No | No |
Collagen concentration | 1-10 mg/mL | 1-10 mg/mL | 1-10 mg/mL |
GAG concentration | 1-10 μg/mL | 1-10 μg/mL | 1-10 μg/mL |
Storage Modulus (G') | 500-1000 Pa | 1-50 KPa | 1-50 KPa |